A genetic mutation changing just one base pair of nucleotides greatly increases risk of a lethal subtype of childhood acute lymphoblastic leukemia.
Idiopathic dilated cardiomyopathy (DCM) was found to have a familial etiology in 30 percent of individuals diagnosed with DCM.
The drug darolutamid, administered with standard androgen-deprivation therapy and docetaxel chemotherapy, increased survival in patients with metastatic hormone-sensitive prostate cancer.
Neural stem cells used in combination with the HER2 inhibitor drug tucatinib improved survival in mice with HER2 positive breast cancer brain metastases.
David Holtzman, ’85 MD, is breaking new ground in identifying, treating, and preventing Alzheimer’s disease and other disorders that affect memory and thinking.